Bone Cancer

Bone Cancer

Bone cancer is a rare type of cancer that starts in the cells of the bones. There are several types, including osteosarcoma, Ewing sarcoma, and chondrosarcoma, each affecting different types of bone tissue. Bone cancer may be primary (originating in the bone) or secondary (cancer that has spread to the bone from other parts of the body, known as bone metastases). Early diagnosis and treatment are crucial for improving outcomes. At Burjeel Cancer Institute, we provide comprehensive care for bone cancer, including surgery, chemotherapy, radiation therapy, and limb-sparing procedures.

Common Symptoms of Bone Cancer include

  • Persistent bone pain that worsens over time
  • Swelling or tenderness near the affected bone
  • Fractures due to weakened bones
  • Fatigue or unexplained weight loss
  • Reduced mobility or limping
  • Swelling or lumps over a bone

Risk Factors for bone cancer include

Risk Factors for bone cancer include

Age

Age

Osteosarcoma and Ewing sarcoma are more common in children and young adults, while chondrosarcoma is more common in adults over 40


Radiation Exposure

Radiation Exposure

Previous radiation therapy increases the risk of developing bone cancer


Inherited Genetic Conditions

Inherited Genetic Conditions

Certain inherited syndromes, such as Li-Fraumeni syndrome, increase the risk of bone cancer


Paget’s Disease of Bone

Paget’s Disease of Bone

This condition, which causes abnormal bone growth, increases the risk of bone cancer in older adults


Bone Marrow Transplant

Bone Marrow Transplant

Patients who have undergone a bone marrow transplant may have a higher risk of developing bone cancer

Diagnostic Procedures

Accurate diagnosis is key to determining the most appropriate treatment for bone cancer. At Burjeel Cancer Institute, we offer a range of diagnostic tools, including:

X-Rays

X-Rays

Often the first imaging test used to detect abnormal bone growths or masses


CT Scan and MRI

CT Scan and MRI

Advanced imaging to assess the size and extent of the tumor, as well as whether the cancer has spread to nearby tissues or organs


Bone Scan

Bone Scan

A nuclear imaging test that detects abnormalities in the bones by using a small amount of radioactive material


PET-CT Scan

PET-CT Scan

Combines positron emission tomography and computed tomography to detect cancer spread to other parts of the body


Biopsy

Biopsy

A sample of tissue is taken from the bone tumor to confirm the diagnosis and identify the type of bone cancer


Treatment Options

Treatment Options

Surgical Treatment

Surgical Treatment

  • Limb-Sparing Surgery: For many bone cancers, the tumor can be removed while preserving the limb. Reconstruction with bone grafts or metal implants may be performed after the tumor is removed.
  • Amputation: In some cases where limb-sparing surgery is not possible, amputation may be necessary to completely remove the cancer and prevent its spread.
  • Pelvic and Spinal Surgery: Specialized surgeries to remove tumors in complex areas like the pelvis and spine while preserving function.
Targeted Therapy

Targeted Therapy

  • Targeted Therapy: Drugs like denosumab may be used in certain types of bone cancers, such as giant cell tumors, to inhibit the growth of cancer cells.
  • Immunotherapy: While not commonly used for bone cancer, certain types of immunotherapy may be explored in clinical trials for patients with specific genetic markers or advanced cases.
Radiation Therapy

Radiation Therapy

  • External Beam Radiation Therapy (EBRT): High-energy radiation is used to target and destroy cancer cells, especially in cases where surgery is not possible or in combination with other treatments.
  • Proton Beam Therapy: This type of radiation delivers precise doses of radiation to the tumor, sparing surrounding healthy tissue, and is particularly useful in treating bone cancer in sensitive areas like the spine or pelvis.
Chemotherapy

Chemotherapy

  • Neoadjuvant Chemotherapy: Chemotherapy is often given before surgery to shrink the tumor and increase the chances of successful surgery.
  • Adjuvant Chemotherapy: After surgery, chemotherapy is used to destroy any remaining cancer cells and reduce the risk of recurrence.
  • Systemic Chemotherapy: Drugs such as methotrexate, doxorubicin, and cisplatin are commonly used in the treatment of osteosarcoma and Ewing sarcoma.
Surgical Treatment

Surgical Treatment

  • Limb-Sparing Surgery: For many bone cancers, the tumor can be removed while preserving the limb. Reconstruction with bone grafts or metal implants may be performed after the tumor is removed.
  • Amputation: In some cases where limb-sparing surgery is not possible, amputation may be necessary to completely remove the cancer and prevent its spread.
  • Pelvic and Spinal Surgery: Specialized surgeries to remove tumors in complex areas like the pelvis and spine while preserving function.

Multidisciplinary Approach

Bone cancer care at Burjeel Cancer Institute involves collaboration among a team of specialists, ensuring that every aspect of the patient's care is addressed. Our team includes:

  • Orthopedic Oncologists
  • Medical Oncologists
  • Radiation Oncologists
  • Pediatric Oncologists (for pediatric bone cancer)
  • Reconstructive Surgeons
  • Radiologists
  • Pathologists
  • Oncology Nurses
  • Physical Therapists
  • Palliative Care Specialists

This multidisciplinary approach ensures that patients receive comprehensive and personalized care at every stage of their treatment


Multidisciplinary Approach

Supportive Care and Patient Services

Supportive Care and Patient Services

Physical Rehabilitation

Physical Rehabilitation

After surgery, especially after limb-sparing surgery or amputation, rehabilitation is crucial to help patients regain strength, mobility, and function



Prosthetics and Orthotics

Prosthetics and Orthotics

For patients undergoing amputation, we offer access to advanced prosthetics and orthotics to improve mobility and quality of life



Pain Management

Pain Management

A comprehensive pain management plan is essential for bone cancer patients, particularly those undergoing surgery or radiation therapy



Palliative Care

Palliative Care

Symptom management and quality-of-life support for patients with advanced or metastatic bone cancer



Psychosocial Support

Psychosocial Support

Counseling services to help patients and their families cope with the emotional and psychological challenges of a bone cancer diagnosis



Nutritional Counseling

Nutritional Counseling

Tailored dietary advice to help patients maintain strength and manage side effects during chemotherapy or surgery



Survivorship Program

Survivorship Program

Ongoing care and monitoring for patients who have completed treatment, focusing on long-term health and recurrence prevention

Meet Our Experts

Mohammed Ramzan 

Dr. Mohammed Ramzan 

Pediatric Hematology & Bone Marrow Transplantation 

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Raed Faisal Al Saruri

Dr. Raed Faisal Al Saruri

Orthopedics Oncology 

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Nicholas Wyon  

Dr. Nicholas Wyon  

Intensive Care Unit

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Wessam Alkrad

Dr. Wessam Alkrad

Medical Oncology

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Patient Journey

Initial Consultation

Initial Consultation

A comprehensive evaluation with the bone cancer care team, including diagnostic imaging and tests to assess the extent of the disease



Personalized Treatment Plan

Personalized Treatment Plan

Based on the patient’s diagnosis, preferences, and overall health, a customized treatment plan is developed



Treatment and Support

Treatment and Support

Patients undergo surgery, chemotherapy, or radiation therapy, supported by a multidisciplinary team and personalized supportive care services



Follow-Up Care

Follow-Up Care

After treatment, patients receive regular follow-ups to monitor their recovery, assess treatment response, and manage long-term health concerns